Complement Mediated Endothelial Damage in Thrombotic Microangiopathies

Thrombotic microangiopathies (TMA) constitute a group of different disorders that have a common underlying mechanism: the endothelial damage. These disorders may exhibit different mechanisms of endothelial injury depending on the pathological trigger. However, over the last decades, the potential ro...

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Detalhes bibliográficos
Main Authors: Miquel Blasco, Elena Guillén-Olmos, Maribel Diaz-Ricart, Marta Palomo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-04-01
Colecção:Frontiers in Medicine
Assuntos:
C5b-9 deposition
complement system activation
complement blockade
endothelia cells
membrane attack complex
thrombotic microangiopathies
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmed.2022.811504/full
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