Chronic Cannabidiol Administration Attenuates Skeletal Muscle De Novo Ceramide Synthesis Pathway and Related Metabolic Effects in a Rat Model of High-Fat Diet-Induced Obesity

Numerous studies showed that sustained obesity results in accumulation of bioactive lipid derivatives in several tissues, including skeletal muscle, which further contributes to the development of metabolic disturbances and insulin resistance (IR). The latest data indicate that a potential factor re...

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Main Authors: Patrycja Bielawiec, Ewa Harasim-Symbor, Karolina Konstantynowicz-Nowicka, Klaudia Sztolsztener, Adrian Chabowski
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2020-08-01
Serija:Biomolecules
Teme:
cannabidiol
obesity
insulin resistance
ceramide
sphingolipids
glucose
Online dostop:https://www.mdpi.com/2218-273X/10/9/1241
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