A potential association between IL‐3 and type I and III interferons in systemic lupus erythematosus

Abstract Objectives Plasmacytoid dendritic cells (pDCs), through the production of type 1 interferons (IFNs) and other cytokines, are major contributors to systemic lupus erythematosus (SLE) pathogenesis. IL‐3 promotes pDC survival, but its role in SLE is not well characterised. This study investiga...

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Detalhes bibliográficos
Main Authors: Shereen Oon, Katherine Monaghan, Milica Ng, Alberta Hoi, Eric Morand, Gino Vairo, Eugene Maraskovsky, Andrew D Nash, Ian P Wicks, Nicholas J Wilson
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2019-01-01
Colecção:Clinical & Translational Immunology
Assuntos:
cytokines
gene signature
immunological disorders
interferons
interleukin-3
systemic lupus erythematosus
Acesso em linha:https://doi.org/10.1002/cti2.1097
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