Non-redundant Functions of IL-6 Produced by Macrophages and Dendritic Cells in Allergic Airway Inflammation

Asthma is a common inflammatory disease of the airway caused by a combination of genetic and environmental factors and characterized by airflow obstruction, wheezing, eosinophilia, and neutrophilia of lungs and sputum. Similar to other proinflammatory cytokines, IL-6 is elevated in asthma and plays...

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Autori principali: Ekaterina O. Gubernatorova, Ekaterina A. Gorshkova, Olga A. Namakanova, Ruslan V. Zvartsev, Juan Hidalgo, Marina S. Drutskaya, Alexei V. Tumanov, Sergei A. Nedospasov
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018-11-01
Serie:Frontiers in Immunology
Soggetti:
HDM-induced asthma
eosinophils
neutrophils
mouse models
house dust mite (HDM)
Accesso online:https://www.frontiersin.org/article/10.3389/fimmu.2018.02718/full
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