The Intrinsically Disordered W Protein Is Multifunctional during Henipavirus Infection, Disrupting Host Signalling Pathways and Nuclear Import

Nipah and Hendra viruses are highly pathogenic, zoonotic henipaviruses that encode proteins that inhibit the host’s innate immune response. The W protein is one of four products encoded from the P gene and binds a number of host proteins to regulate signalling pathways. The W protein is intrinsicall...

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Main Authors: Sofiya Tsimbalyuk, Emily M. Cross, Mikayla Hoad, Camilla M. Donnelly, Justin A. Roby, Jade K. Forwood
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2020-08-01
Series:Cells
Assuntos:
intrinsically disordered
W protein
henipaviruses
STAT
IRF-3
Acceso en liña:https://www.mdpi.com/2073-4409/9/8/1913
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