The Intrinsically Disordered W Protein Is Multifunctional during Henipavirus Infection, Disrupting Host Signalling Pathways and Nuclear Import

Nipah and Hendra viruses are highly pathogenic, zoonotic henipaviruses that encode proteins that inhibit the host’s innate immune response. The W protein is one of four products encoded from the P gene and binds a number of host proteins to regulate signalling pathways. The W protein is intrinsicall...

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Bibliographische Detailangaben
Hauptverfasser: Sofiya Tsimbalyuk, Emily M. Cross, Mikayla Hoad, Camilla M. Donnelly, Justin A. Roby, Jade K. Forwood
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2020-08-01
Schriftenreihe:Cells
Schlagworte:
intrinsically disordered
W protein
henipaviruses
STAT
IRF-3
Online Zugang:https://www.mdpi.com/2073-4409/9/8/1913
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