High frequency oscillations play important roles in development of epileptogenesis/ictogenesis via activation of astroglial signallings

To explore developmental processes of epileptogenesis/ictogenesis and pathophysiology of carbamazepine-resistant epilepsy, we determined effects of high-frequency-oscillation (HFO) on glutamatergic tripartite-synaptic transmission, astroglial expression of connexin43, and intracellular Erk- and Akt-...

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Detalhes bibliográficos
Main Authors: Kouji Fukuyama, Motohiro Okada
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-05-01
Colecção:Biomedicine & Pharmacotherapy
Assuntos:
Autosomal dominant sleep-related hypermotor epilepsy
L-glutamate
Hemichannel
Extracellular signal-regulated kinase
Protein kinase B
Epileptogenesis
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0753332222002347
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