Identification of Anti-Persister Activity against Uropathogenic Escherichia coli from a Clinical Drug Library

Uropathogenic E. coli is a major cause of urinary tract infections (UTIs), but current antibiotics do not always effectively clear the persistent infection. To identify drugs that eliminate uropathogenic E. coli persisters, we screened a clinical drug library consisting of 1524 compounds using high...

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Hauptverfasser: Hongxia Niu, Peng Cui, Wanliang Shi, Shuo Zhang, Jie Feng, Yong Wang, David Sullivan, Wenhong Zhang, Bingdong Zhu, Ying Zhang
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2015-05-01
Schriftenreihe:Antibiotics
Schlagworte:
Escherichia coli
persisters
anti-persister activity
clinical drug library
urinary tract infection
Online Zugang:http://www.mdpi.com/2079-6382/4/2/179
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