5-(1<i>H</i>-Indol-3-ylmethylene)-4-oxo-2-thioxothiazolidin-3-yl)alkancarboxylic Acids as Antimicrobial Agents: Synthesis, Biological Evaluation, and Molecular Docking Studies

Background: Infectious diseases symbolize a global consequential strain on public health security and impact on the socio-economic stability all over the world. The increasing resistance to the current antimicrobial treatment has resulted in crucial need for the discovery and development of novel en...

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Main Authors: Volodymyr Horishny, Victor Kartsev, Athina Geronikaki, Vasyl Matiychuk, Anthi Petrou, Jasmina Glamoclija, Ana Ciric, Marina Sokovic
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-04-01
Colecção:Molecules
Assuntos:
indole
antimicrobial
antifungal
<i>E. coli</i> MurB
<i>Candida albicans</i> 14<sup>α</sup>-demethylase
CYP51
Acesso em linha:https://www.mdpi.com/1420-3049/25/8/1964
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