Repositioning of the Angiotensin II Receptor Antagonist Candesartan as an Anti-Inflammatory Agent With NLRP3 Inflammasome Inhibitory Activity

Aberrant activation of the NLRP3 inflammasome promotes the pathogenesis of many inflammatory diseases. The development of the NLRP3 inflammasome inhibitors from existing drugs for new therapeutic purposes is becoming more important. Candesartan is an angiotensin II receptor antagonist widely used as...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wen-Yu Lin, Lan-Hui Li, Ya-Yun Hsiao, Wei-Ting Wong, Hsiao-Wen Chiu, Hsien-Ta Hsu, Yi-Jen Peng, Chen-Lung Ho, Oleg V. Chernikov, Shu-Meng Cheng, Shih-Ping Yang, Kuo-Feng Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-05-01
Colecção:Frontiers in Immunology
Assuntos:
NLRP3 inflammasome
candesartan
angiotensin II receptor antagonist
drug repositioning
peritonitis
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2022.870627/full
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados