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Laquinimod, a quinoline-3-carboxamide, induces type II myeloid cells that modulate central nervous system autoimmunity.

Laquinimod is a novel oral drug that is currently being evaluated for the treatment of relapsing-remitting (RR) multiple sclerosis (MS). Using the animal model for multiple sclerosis, experimental autoimmune encephalomyelitis (EAE), we examined how laquinimod promotes immune modulation. Oral laquini...

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Detalhes bibliográficos
Main Authors: Ulf Schulze-Topphoff, Aparna Shetty, Michel Varrin-Doyer, Nicolas Molnarfi, Sharon A Sagan, Raymond A Sobel, Patricia A Nelson, Scott S Zamvil
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2012-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3316495?pdf=render
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