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RNF7 inhibits apoptosis and sunitinib sensitivity and promotes glycolysis in renal cell carcinoma via the SOCS1/JAK/STAT3 feedback loop

Abstract Background RING finger protein 7 (RNF7) is a highly conserved protein that functions as an E3 ubiquitin ligase. RNF7 overexpression is indicated in multiple human cancers, but its role in renal cell carcinoma (RCC) and the mechanisms underlying how it regulates the initiation and progressio...

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書誌詳細
主要な著者: Chengwu Xiao, Wei Zhang, Meimian Hua, Huan Chen, Bin Yang, Ye Wang, Qing Yang
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2022-05-01
シリーズ:Cellular & Molecular Biology Letters
主題:
オンライン・アクセス:https://doi.org/10.1186/s11658-022-00337-5
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