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Human adipose-tissue derived stromal cells in combination with hypoxia effectively support ex vivo expansion of cord blood haematopoietic progenitors.

The optimisation of haematopoietic stem and progenitor cell expansion is on demand in modern cell therapy. In this work, haematopoietic stem/progenitor cells (HSPCs) have been selected from unmanipulated cord blood mononuclear cells (cbMNCs) due to adhesion to human adipose-tissue derived stromal ce...

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Main Authors: Elena R Andreeva, Irina V Andrianova, Elena V Sotnezova, Sergey V Buravkov, Polina I Bobyleva, Yury A Romanov, Ludmila B Buravkova
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2014-01-01
叢編:PLoS ONE
在線閱讀:http://europepmc.org/articles/PMC4412539?pdf=render
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