Targeting the Id1-Kif11 Axis in Triple-Negative Breast Cancer Using Combination Therapy

The basic helix-loop-helix (bHLH) transcription factors inhibitor of differentiation 1 (<i>Id1</i>) and inhibitor of differentiation 3 <i>(Id3)</i> (referred to as <i>Id</i>) have an important role in maintaining the cancer stem cell (CSC) phenotype in the triple-...

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Autori principali: Archana P. Thankamony, Reshma Murali, Nitheesh Karthikeyan, Binitha Anu Varghese, Wee S. Teo, Andrea McFarland, Daniel L. Roden, Holly Holliday, Christina Valbirk Konrad, Aurelie Cazet, Eoin Dodson, Jessica Yang, Laura A. Baker, Jason T. George, Herbert Levine, Mohit Kumar Jolly, Alexander Swarbrick, Radhika Nair
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2020-09-01
Serie:Biomolecules
Soggetti:
cancer stem cells
chemoresistance
self-renewal
combination therapy
<i>Id1</i>
<i>Kif11</i>
Accesso online:https://www.mdpi.com/2218-273X/10/9/1295
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