Targeting the Id1-Kif11 Axis in Triple-Negative Breast Cancer Using Combination Therapy

The basic helix-loop-helix (bHLH) transcription factors inhibitor of differentiation 1 (<i>Id1</i>) and inhibitor of differentiation 3 <i>(Id3)</i> (referred to as <i>Id</i>) have an important role in maintaining the cancer stem cell (CSC) phenotype in the triple-...

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Hauptverfasser: Archana P. Thankamony, Reshma Murali, Nitheesh Karthikeyan, Binitha Anu Varghese, Wee S. Teo, Andrea McFarland, Daniel L. Roden, Holly Holliday, Christina Valbirk Konrad, Aurelie Cazet, Eoin Dodson, Jessica Yang, Laura A. Baker, Jason T. George, Herbert Levine, Mohit Kumar Jolly, Alexander Swarbrick, Radhika Nair
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2020-09-01
Schriftenreihe:Biomolecules
Schlagworte:
cancer stem cells
chemoresistance
self-renewal
combination therapy
<i>Id1</i>
<i>Kif11</i>
Online Zugang:https://www.mdpi.com/2218-273X/10/9/1295
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