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BET protein inhibition regulates cytokine production and promotes neuroprotection after spinal cord injury

Abstract Background Spinal cord injury (SCI) usually causes a devastating lifelong disability for patients. After a traumatic lesion, disruption of the blood-spinal cord barrier induces the infiltration of macrophages into the lesion site and the activation of resident glial cells, which release cyt...

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Detalhes bibliográficos
Main Authors: Judith Sánchez-Ventura, Jesús Amo-Aparicio, Xavier Navarro, Clara Penas
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-06-01
Colecção:Journal of Neuroinflammation
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Acesso em linha:http://link.springer.com/article/10.1186/s12974-019-1511-7
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