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Circulating IgGs in Type 2 Diabetes with Atrial Fibrillation Induce IP3-Mediated Calcium Elevation in Cardiomyocytes

Summary: Higher risk of cardiac arrhythmias including atrial fibrillation (AF) associates with type 2 diabetes mellitus (T2DM) with the underlying mechanism largely unknown. The present study reported a subset of circulating immunoglobulin G autoantibodies (IgGs) from patients with T2DM with AF (T2D...

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Detalhes bibliográficos
Main Authors: Yanhong Luo, Xian Liu, Ruilian Ma, Yigang Wang, Mark Zimering, Zui Pan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020-04-01
Colecção:iScience
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2589004220302200
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