Investigations Into Bioenergetic Neuroprotection of Cone Photoreceptors: Relevance to Retinitis Pigmentosa

Recent studies suggest cone degeneration in retinitis pigmentosa (RP) may result from intracellular energy depletion. We tested the hypothesis that cones die when depleted of energy by examining the effect of two bioenergetic, nutraceutical agents on cone survival. The study had three specific aims:...

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Bibliographic Details
Main Authors: Daniel S. Narayan, Glyn Chidlow, John P. M. Wood, Robert J. Casson
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Neuroscience
Subjects:
rd1 mouse
retinitis pigmentosa
cone photoreceptor
bioenergetic neuroprotection
creatine
nutraceutical
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01234/full
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