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A randomised, double-blind, parallel-group trial to assess mercaptopurine versus placebo to prevent or delay recurrence of Crohn’s disease following surgical resection (TOPPIC)
Background: Crohn’s disease (CD) is a chronic, relapsing, inflammatory bowel disease. Up to 65% of patients with CD require an operation to control the disease within 10 years. Both endoscopic and clinical recurrence is common within 2 years of operation, with re-operation rates cumulating at 5% of...
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Principais autores: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
NIHR Journals Library
2017-09-01
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coleção: | Efficacy and Mechanism Evaluation |
Assuntos: | |
Acesso em linha: | https://doi.org/10.3310/eme04040 |
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