The prevalence of PAI-1 4G/5G polymorphism in women with fetal loss: First data for a Serbian population

Background: Plasminogen activator inhibitor 1 (PAI-1) is an inhibitor of fibrinolysis. The PAI-1 4G/5G polymorphism is associated with elevated plasma levels of PAI-1. Overexpression of PAI-1 and impaired fibrinolysis in homozygous carriers of the 4G/4G PAI polymorphism may lead to abnormal placenta...

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Hauptverfasser: Đorđević Valentina, Gvozdenov Maja, Pruner Iva, Kovač Mirjana, Tomić Branko, Stanković Marija, Radojković Dragica
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society of Medical Biochemists of Serbia, Belgrade 2014-01-01
Schriftenreihe:Journal of Medical Biochemistry
Schlagworte:
pai-1 4g/5g polymorphism
plasminogen activator inhibitor-1
fetal loss
Online Zugang:https://scindeks-clanci.ceon.rs/data/pdf/1452-8258/2014/1452-82581402203Q.pdf
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