Toxicity Study of 28-Day Subcutaneous Injection of Arctigenin in Beagle Dogs

Our previous studies have investigated the systematic pharmacokinetic characteristics, biological activities, and toxicity of arctigenin. In this research, the potential toxicities of arctigenin in beagle dogs were investigated via repeated 28-day subcutaneous injections. Beagle dogs were randomly d...

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Main Authors: Jie Li, Yun-gang Lv, Li-hong Pan, Fang-fang Yao, Tao Peng, Yu-jun Tan, Gui-Min Zhang, Zhong Liu, Jing-chun Yao, Yu-shan Ren
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019-10-01
Serier:Frontiers in Pharmacology
Fag:
arctigenin
toxicity
toxicokinetics
NOAEL
inflammation
Online adgang:https://www.frontiersin.org/article/10.3389/fphar.2019.01218/full
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