Expression of genes related to anti-inflammatory pathways are modified among farmers' children.

BACKGROUND: The hygiene hypothesis states that children exposed to higher loads of microbes such as farmers' children suffer less from allergies later in life. Several immunological mechanisms underpinning the hygiene hypothesis have been proposed such as a shift in T helper cell balance, T reg...

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Main Authors: Remo Frei, Caroline Roduit, Christian Bieli, Susanne Loeliger, Marco Waser, Annika Scheynius, Marianne van Hage, Göran Pershagen, Gert Doekes, Josef Riedler, Erika von Mutius, Felix Sennhauser, Cezmi A Akdis, Charlotte Braun-Fahrländer, Roger P Lauener, as part of the PARSIFAL study team
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3946278?pdf=render
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