Loading...

CLN3 deficient cells display defects in the ARF1-Cdc42 pathway and actin-dependent events.

Juvenile Batten disease (juvenile neuronal ceroid lipofuscinosis, JNCL) is a devastating neurodegenerative disease caused by mutations in CLN3, a protein of undefined function. Cell lines derived from patients or mice with CLN3 deficiency have impairments in actin-regulated processes such as endocyt...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Mark L Schultz, Luis Tecedor, Colleen S Stein, Mark A Stamnes, Beverly L Davidson
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2014-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC4008583?pdf=render
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!