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Hepatic safety of ambrisentan alone and in combination with tadalafil: a post-hoc analysis of the AMBITION trial

Treatment with endothelin receptor antagonists (ERA) can result in adverse hepatic effects in patients with pulmonary arterial hypertension (PAH). We evaluated the hepatic safety of ambrisentan (ABS), an ERA, used as monotherapy, or with tadalafil (TAD), a phosphodiesterase-5 (PDE5) inhibitor as ini...

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Detalhes bibliográficos
Main Authors: Krishna R. Patel, Christiana J. Blair, James D. Tislow
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publishing 2018-08-01
Colecção:Pulmonary Circulation
Acesso em linha:https://doi.org/10.1177/2045894018797273
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