Induction of humoral and cellular immune responses against the HIV-1 envelope protein using γ-retroviral virus-like particles

<p>Abstract</p> <p>This study evaluates the immunogenicity of the HIV envelope protein (env) in mice presented either attached to γ-retroviral virus-like-particles (VLPs), associated with cell-derived microsomes or as solubilized recombinant protein (gp160). The magnitude and polyf...

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Bibliographic Details
Main Authors: Purcell Damian FJ, Center Robert J, Pedersen Finn S, Bahrami Shervin, Melchjorsen Jesper, Wheatley Adam, Kirkegaard Tea, Ostergaard Lars, Duch Mogens, Tolstrup Martin
Format: Artigo
Language:Inglês
Published: BMC 2011-08-01
Series:Virology Journal
Subjects:
HIV-1 envelope protein
Virus-like particles
γ-retroviruses
immunity
Online Access:http://www.virologyj.com/content/8/1/381
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