The related transcriptional enhancer factor-1 isoform, TEAD4(216), can repress vascular endothelial growth factor expression in mammalian cells.

Increased cellular production of vascular endothelial growth factor (VEGF) is responsible for the development and progression of multiple cancers and other neovascular conditions, and therapies targeting post-translational VEGF products are used in the treatment of these diseases. Development of met...

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Detalhes bibliográficos
Main Authors: Binoy Appukuttan, Trevor J McFarland, Andrew Stempel, Jean B Kassem, Matthew Hartzell, Yi Zhang, Derek Bond, Kelsey West, Reid Wilson, Andrew Stout, Yuzhen Pan, Hoda Ilias, Kathryn Robertson, Michael L Klein, David Wilson, Justine R Smith, J Timothy Stout
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2012-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3382240?pdf=render
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