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Identification of CD4+ T cell epitopes in C. burnetii antigens targeted by antibody responses.
Coxiella burnetii is an obligate intracellular gram-negative bacterium that causes acute Q fever and chronic infections in humans. A killed, whole cell vaccine is efficacious, but vaccination can result in severe local or systemic adverse reactions. Although T cell responses are considered pivotal f...
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Hauptverfasser: | , , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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Public Library of Science (PLoS)
2011-03-01
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Schriftenreihe: | PLoS ONE |
Online Zugang: | http://europepmc.org/articles/PMC3057979?pdf=render |
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