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Identification of CD4+ T cell epitopes in C. burnetii antigens targeted by antibody responses.

Coxiella burnetii is an obligate intracellular gram-negative bacterium that causes acute Q fever and chronic infections in humans. A killed, whole cell vaccine is efficacious, but vaccination can result in severe local or systemic adverse reactions. Although T cell responses are considered pivotal f...

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Detalhes bibliográficos
Main Authors: Chen Chen, Courtney Dow, Peng Wang, John Sidney, Amanda Read, Allen Harmsen, James E Samuel, Bjoern Peters
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2011-03-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3057979?pdf=render
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