N-Terminal Domain of Feline Calicivirus (FCV) Proteinase-Polymerase Contributes to the Inhibition of Host Cell Transcription

Feline Calicivirus (FCV) infection results in the inhibition of host protein synthesis, known as “shut-off”. However, the precise mechanism of shut-off remains unknown. Here, we found that the FCV strain 2280 proteinase-polymerase (PP) protein can suppress luciferase reporter gene expression driven...

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Detalhes bibliográficos
Main Authors: Hongxia Wu, Shaopo Zu, Xue Sun, Yongxiang Liu, Jin Tian, Liandong Qu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2016-07-01
Colecção:Viruses
Assuntos:
FCV
PP
inhibition
key function sites
transcription
Acesso em linha:http://www.mdpi.com/1999-4915/8/7/199
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