TASK-1 potassium channel is not critically involved in mediating hypoxic pulmonary vasoconstriction of murine intra-pulmonary arteries.

The two-pore domain potassium channel KCNK3 (TASK-1) is expressed in rat and human pulmonary artery smooth muscle cells. There, it is associated with hypoxia-induced signalling, and its dysfunction is linked to pathogenesis of human pulmonary hypertension. We here aimed to determine its role in hypo...

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מידע ביבליוגרפי
Main Authors: Ghulam Murtaza, Petra Mermer, Anna Goldenberg, Uwe Pfeil, Renate Paddenberg, Nobert Weissmann, Guenter Lochnit, Wolfgang Kummer
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science (PLoS) 2017-01-01
סדרה:PLoS ONE
גישה מקוונת:http://europepmc.org/articles/PMC5354433?pdf=render
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