REPARATION SYSTEM GENES: POPULATION DIFFERENCES IN HEREDITARY OVARIAN AND BREAST CANCER DETERMINED BY NEXT-GENERATION SEQUENCING

Introduction. Development of hereditary ovarian cancer (OC) and breast cancer (BC) is caused by genetic abnormalities in the DNA reparation system consisting of more than 100 genes. However, currently in the majority of medical centers in Russia, diagnosis of hereditary OC and BC consists of determi...

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Main Authors: O. I. Brovkina, M. G. Gordiev, R. F. Enikeev, M. O. Druzhkov, L. Kh. Shigapova, E. I. Shagimardanova, O. А. Gusev, V. V. Kosiy, D. S. Khodyrev, A. G. Kedrova, R. Sh. Khasanov, A. G. Nikitin
Formato: Artigo
Idioma:Russo
Publicado em: ABV-press 2017-06-01
Colecção:Opuholi Ženskoj Reproduktivnoj Sistemy
Assuntos:
hereditary breast cancer
hereditary ovarian cancer
mutation
brca1/brca2 genes
genes of dna reparation system
Acesso em linha:https://ojrs.abvpress.ru/ojrs/article/view/544
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