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TGF-β and iron differently alter HBV replication in human hepatocytes through TGF-β/BMP signaling and cellular microRNA expression.

The nature of host-virus interactions in hepatitis B virus infection is incompletely understood. Since soluble factors, e.g., cytokines and metals, may exacerbate liver injury in chronic hepatitis, we considered that defining the effects of receptor-mediated signaling upon viral replication will be...

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Main Authors: Sun O Park, Mukesh Kumar, Sanjeev Gupta
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC3377643?pdf=render
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