Molecular Characteristics of m6A Regulators and Tumor Microenvironment Infiltration in Soft Tissue Sarcoma: A Gene-Based Study

Background: N6-methyladenosine (m6A) methylation played a key role in tumor growth. However, the relationship between m6A and soft tissue sarcoma (STS) was still unclear.Methods: The characterization and patterns of m6A modification in STS (TCGA-SARC and GSE17674) were analyzed comprehensively throu...

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Main Authors: Kang-Wen Xiao, Zhi-Qiang Yang, Xin Yan, Zhi-Bo Liu, Min Yang, Liang-Yu Guo, Lin Cai
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-04-01
Colecção:Frontiers in Bioengineering and Biotechnology
Assuntos:
m6A
soft tissue sarcoma
immunotherapy
tumor microenvironment
survival
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fbioe.2022.846812/full
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