Mesenchymal stem cell transplantation ameliorates Sjögren’s syndrome via suppressing IL-12 production by dendritic cells

Abstract Background Mesenchymal stem cells (MSCs) have been demonstrated to be effective in treating autoimmune diseases including Sjögren’s syndrome (SS). We aim to compare the effects of MSC transplantation (MSCT) and the role of serum interleukin-12 (IL-12) in SS. Methods IL-12 levels were measur...

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Main Authors: Bingyu Shi, Jingjing Qi, Genhong Yao, Ruihai Feng, Zhuoya Zhang, Dandan Wang, Chen Chen, Xiaojun Tang, Liwei Lu, Wanjun Chen, Lingyun Sun
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2018-11-01
Series:Stem Cell Research & Therapy
Assuntos:
Mesenchymal stem cells
Sjögren’s syndrome
Interleukin-12
Acceso en liña:http://link.springer.com/article/10.1186/s13287-018-1023-x
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