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Endothelial cell-specific molecule 2 (ECSM2) localizes to cell-cell junctions and modulates bFGF-directed cell migration via the ERK-FAK pathway.

Despite its first discovery by in silico cloning of novel endothelial cell-specific genes a decade ago, the biological functions of endothelial cell-specific molecule 2 (ECSM2) have only recently begun to be understood. Limited data suggest its involvement in cell migration and apoptosis. However, t...

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Autori principali: Chunwei Shi, Jia Lu, Wen Wu, Fanxin Ma, Joseph Georges, Hanju Huang, James Balducci, Yongchang Chang, Yao Huang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2011-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3123356?pdf=render
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