Cytotoxic Desulfated Saponin from Holothuria atra Predicted to Have High Binding Affinity to the Oncogenic Kinase PAK1: A Combined In Vitro and In Silico Study

Sea cucumbers have long been utilized in foods and Asiatic folk medicines for their nutritive and health benefits. Herein, three sea cucumber species were investigated and Holothuria atra showed the highest cytotoxicity among these. Next, a desulfated saponin, desulfated echinoside B (DEB), was puri...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Md Shahinozzaman, Takahiro Ishii, Ryo Takano, Mohammad A. Halim, Md Amzad Hossain, Shinkichi Tawata
Formato: Artigo
Idioma:Inglês
Publicado em: Österreichische Apotheker-Verlagsgesellschaft m. b. H. 2018-08-01
Colecção:Scientia Pharmaceutica
Assuntos:
Holothuria atra
desulfated echinoside B
molecular docking
molecular dynamics
p21-activated kinase 1
Acesso em linha:http://www.mdpi.com/2218-0532/86/3/32
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados