Investigating rectal toxicity associated dosimetric features with deformable accumulated rectal surface dose maps for cervical cancer radiotherapy

Abstract Background Better knowledge of the dose-toxicity relationship is essential for safe dose escalation to improve local control in cervical cancer radiotherapy. The conventional dose-toxicity model is based on the dose volume histogram, which is the parameter lacking spatial dose information....

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Main Authors: Jiawei Chen, Haibin Chen, Zichun Zhong, Zhuoyu Wang, Brian Hrycushko, Linghong Zhou, Steve Jiang, Kevin Albuquerque, Xuejun Gu, Xin Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-07-01
Colecção:Radiation Oncology
Assuntos:
Rectum toxicity prediction
Machine learning
Dose accumulation
Deformable registration
Cervical cancer
Acesso em linha:http://link.springer.com/article/10.1186/s13014-018-1068-0
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