Tumor Microenvironmental Signaling Elicits Epithelial-Mesenchymal Plasticity through Cooperation with Transforming Genetic Events

Epithelial-to-mesenchymal transition (EMT) facilitates the escape of epithelial cancer cells from the primary tumor site, which is a key event early in metastasis. Here, we explore how extrinsic, tumor microenvironmental cytokines cooperate with intrinsic, genetic changes to promote EMT in human mam...

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Main Authors: Damian J. Junk, Rocky Cipriano, Benjamin L. Bryson, Hannah L. Gilmore, Mark W. Jackson
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2013-09-01
Sraith:Neoplasia: An International Journal for Oncology Research
Rochtain Ar Líne:http://www.sciencedirect.com/science/article/pii/S1476558613800206
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