Acquired Resistance to Antiangiogenic Therapies in Hepatocellular Carcinoma Is Mediated by Yes‐Associated Protein 1 Activation and Transient Expansion of Stem‐Like Cancer Cells

Induction of neoangiogenesis is a hallmark feature during disease progression of hepatocellular carcinoma (HCC). Antiangiogenetic compounds represent a mainstay of therapeutic approaches; however, development of chemoresistance is observed in the majority of patients. Recent findings suggest that tu...

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Hlavní autoři: Darko Castven, Carolin Czauderna, Diana Becker, Sharon Pereira, Jennifer Schmitt, Arndt Weinmann, Viral Shah, Jovana Hajduk, Friederike Keggenhoff, Harald Binder, Tobias Keck, Stefanie Heilmann‐Heimbach, Marcus A. Wörns, Snorri S. Thorgeirsson, Kai Breuhahn, Peter R. Galle, Jens U. Marquardt
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley 2022-05-01
Edice:Hepatology Communications
On-line přístup:https://doi.org/10.1002/hep4.1869
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