Liposome-Encapsulated Hemoglobin Ameliorates Impairment of Fear Memory and Hippocampal Dysfunction After Cerebral Ischemia in Rats

Abstract.: Liposome-encapsulated hemoglobin (LEH) has been developed as a blood substitute. In spite of its size (1/30 – 1/40 of erythrocytes), LEH has an oxygen-carrying capacity comparable to erythrocytes. Thus, LEH is expected to carry oxygen into vital organs via collateral routes during ischemi...

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Bibliographic Details
Main Authors: Naobumi Hamadate, Taku Yamaguchi, Aya Sugawara, Hiroko Togashi, Takeshi Izumi, Takayuki Yoshida, Yu Ohmura, Mitsuhiro Yoshioka
Format: Artigo
Language:Inglês
Published: Elsevier 2010-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319308199
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