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Glicoproteína-P, resistência a múltiplas drogas (MDR) e relação estrutura-atividade de moduladores P-glycoprotein and multidrug resistance: structure-activity relationships of modulators

<abstract language="eng">Multidrug resistance, MDR is a major obstacle for cancer chemotherapy. MDR can be reversed by drugs that vary in their chemical structure and main biological activity. Many efforts have been done to overcome MDR based on studies of structure-activity relation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Paula C. Huber, Cintia H. Maruiama, Wanda P. Almeida
Format: Artigo
Sprache:Inglês
Veröffentlicht: Sociedade Brasileira de Química 2010-01-01
Schriftenreihe:Química Nova
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Online Zugang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422010001000027
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