Glicoproteína-P, resistência a múltiplas drogas (MDR) e relação estrutura-atividade de moduladores P-glycoprotein and multidrug resistance: structure-activity relationships of modulators

<abstract language="eng">Multidrug resistance, MDR is a major obstacle for cancer chemotherapy. MDR can be reversed by drugs that vary in their chemical structure and main biological activity. Many efforts have been done to overcome MDR based on studies of structure-activity relation...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Paula C. Huber, Cintia H. Maruiama, Wanda P. Almeida
פורמט: Artigo
שפה:Inglês
יצא לאור: Sociedade Brasileira de Química 2010-01-01
סדרה:Química Nova
נושאים:
P-glycoprotein
multidrug resistance
modulators
גישה מקוונת:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422010001000027
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