Involvement of Wnt7a in the role of M2c microglia in neural stem cell oligodendrogenesis

Abstract Background The participation of microglia in CNS development and homeostasis indicate that these cells are pivotal for the regeneration that occurs after demyelination. The clearance of myelin debris and the inflammatory-dependent activation of local oligodendrocyte progenitor cells in a de...

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Bibliografiska uppgifter
Huvudupphovsmän: Miriam Mecha, Natalia Yanguas-Casás, Ana Feliú, Leyre Mestre, Francisco Javier Carrillo-Salinas, Kristoffer Riecken, Diego Gomez-Nicola, Carmen Guaza
Materialtyp: Artigo
Språk:Inglês
Publicerad: BMC 2020-03-01
Serie:Journal of Neuroinflammation
Ämnen:
Microglia
Neural stem cells
Wnt
β-Catenin
Oligodendrogenesis
Subventricular zone
Länkar:http://link.springer.com/article/10.1186/s12974-020-01734-3
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