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DeepRepeat: direct quantification of short tandem repeats on signal data from nanopore sequencing
Abstract Despite recent improvements in basecalling accuracy, nanopore sequencing still has higher error rates on short-tandem repeats (STRs). Instead of using basecalled reads, we developed DeepRepeat which converts ionic current signals into red-green-blue channels, thus transforming the repeat de...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BMC
2022-04-01
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| 叢編: | Genome Biology |
| 主題: | |
| 在線閱讀: | https://doi.org/10.1186/s13059-022-02670-6 |
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