DeepRepeat: direct quantification of short tandem repeats on signal data from nanopore sequencing

Abstract Despite recent improvements in basecalling accuracy, nanopore sequencing still has higher error rates on short-tandem repeats (STRs). Instead of using basecalled reads, we developed DeepRepeat which converts ionic current signals into red-green-blue channels, thus transforming the repeat de...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Li Fang, Qian Liu, Alex Mas Monteys, Pedro Gonzalez-Alegre, Beverly L. Davidson, Kai Wang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BMC 2022-04-01
Saila:Genome Biology
Gaiak:
Short tandem repeat
Nanopore sequencing
Deep learning
Telomeric repeat
Sarrera elektronikoa:https://doi.org/10.1186/s13059-022-02670-6
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak