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Role of Lamin A/C Gene Mutations in the Signaling Defects Leading to Cardiomyopathies

Nuclear lamin A/C are crucial components of the intricate protein mesh that underlies the inner nuclear membrane and confers mainly nuclear and cytosolic rigidity. However, throughout the years a number of other key physiological processes have been associated with lamins such as modulation of both...

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Hlavní autoři: Andrea Gerbino, Giuseppe Procino, Maria Svelto, Monica Carmosino
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018-09-01
Edice:Frontiers in Physiology
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On-line přístup:https://www.frontiersin.org/article/10.3389/fphys.2018.01356/full
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