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Development of a High Throughput Screen for the Identification of Inhibitors of Peptidoglycan <i>O-</i>Acetyltransferases, New Potential Antibacterial Targets

The <i>O</i>-acetylation of peptidoglycan occurs in many Gram-negative and most Gram-positive pathogens and this modification to the essential wall polymer controls the lytic activity of the autolysins, particularly the lytic transglycosylases, and inhibits that of the lysozymes of innat...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ashley S. Brott, Carys S. Jones, Anthony J. Clarke
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2019-05-01
Saila:Antibiotics
Gaiak:
HTS
Sarrera elektronikoa:https://www.mdpi.com/2079-6382/8/2/65
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