Autologous bone marrow stromal cells are promising candidates for cell therapy approaches to treat bone degeneration in sickle cell disease

Osteonecrosis of the femoral head is a frequent complication in adult patients with sickle cell disease (SCD). To delay hip arthroplasty, core decompression combined with concentrated total bone marrow (BM) treatment is currently performed in the early stages of the osteonecrosis. Cell therapy effic...

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Main Authors: Angélique Lebouvier, Alexandre Poignard, Laura Coquelin-Salsac, Julie Léotot, Yasuhiro Homma, Nicolas Jullien, Philippe Bierling, Frédéric Galactéros, Philippe Hernigou, Nathalie Chevallier, Hélène Rouard
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2015-11-01
Serier:Stem Cell Research
Fag:
Bone marrow stromal cells
Sickle cell disease
Osteonecrosis
Bone regeneration
Online adgang:http://www.sciencedirect.com/science/article/pii/S1873506115001361
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