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Mouse transgenesis in a single locus with independent regulation for multiple fluorophores.
A major barrier to complex experimental design in mouse genetics is the allele problem: combining three or more alleles is time-consuming and inefficient. Here, we solve this problem for transgenic animals with a simple modification of existing BAC transgenesis protocols, and generate triple-colored...
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Auteurs principaux: | , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
Public Library of Science (PLoS)
2012-01-01
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Collection: | PLoS ONE |
Accès en ligne: | http://europepmc.org/articles/PMC3395707?pdf=render |
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