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Mouse transgenesis in a single locus with independent regulation for multiple fluorophores.

A major barrier to complex experimental design in mouse genetics is the allele problem: combining three or more alleles is time-consuming and inefficient. Here, we solve this problem for transgenic animals with a simple modification of existing BAC transgenesis protocols, and generate triple-colored...

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Autors principals: Joseph D Dougherty, Juliet Zhang, Huifen Feng, Shiaoching Gong, Nathaniel Heintz
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2012-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3395707?pdf=render
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